Japanese stock indexes closed lower on Friday . Japanese stocks fell on Friday at the end of trading To make losses in the pharmaceutical, warehousing and precision machinery sectors . Some of the most important and prominent leading stocks also declined .. Nintendo Co Ltd shares fell by 9.2% Konami Corp shares fell by 7.1% Dena Co's share fell by 6.4% . The Japanese Nikkei index also declined strongly at the end of trading It fell by 2.2% .